Institute for Clinical Research Official Portal

Clinical Research Centre

Hospital Tunku Azizah
Kuala Lumpur

WhoWe Are

The diversity of clinical cases and the substantial amount of educational activities related to Paediatrics, Obstetrics and Gynaecology make Hospital Tunku Azizah Kuala Lumpur (HTA) a dynamic and leading centre in the country. It started as Unit Penyelidikan in March 2019.  Clinical Research Centre HTA (CRC HTA) established on 23rd October 2019. This is the 35th in the country to facilitate clinical research activities in MOH. Its vision is to become the hub of clinical research, especially in the fields of Paediatrics, Obstetrics and Gynaecology by driving the culture of research and innovation among the staff in this hospital. CRC HTA's mission is to facilitate the conduct of high impact, translational and ethical clinical research in fields related to Paediatrics and O&G while their objective is to encourage, facilitate and supervise researchers to produce scientifically valid and ethically sound clinical research.

OurTeam

NAME POSITION QUALIFICATION EMAIL
Dr. Asiah Kassim Head, Consultant Paediatrician and Paediatric Respiratory
MBBS, M Paed (Mal) asiahkassim@moh.gov.my 
Dr. Maria Kamal Medical Officer (Admin Manager) MBBChBAO (Ire) maria.kamal@moh.gov.my 
Dr. Lui Sze Chiang Medical Officer MBBS, MOHRE (Mal) luiszechiang@moh.gov.my 
Dr. Lee Ching Hai Medical Officer MBBChBAO (Ire) lee.chinghai@moh.gov.my 
Dr. Then Moli Othayamoorthy Medical Officer MD, MPH (Mal) drmoli@moh.gov.my 
Dr. Fatimah AZ Zaharah Bt Suhaimi Medical Officer MBBS (MSU) fatimah.zaharah@moh.gov.my 
Dr. Nur Izyani Abdul Halim Medical Officer
MD (USM) nurizyani.halim@moh.gov.my 
Fauziah Ripin @ Mat Nor Community Nurse Certificate in Midwifery fauziah.ripin@moh.gov.my 

 

Project Highlights

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NMRR-19-3887-52245 Nasopharyngeal Carriage of Streptococcus Pneumoniae in Healthy population in Malaysia
NMRR-19-3889-51527 Invasive pneumococcal disease among children 5 years old and below admitted into Malaysian public hospitals
NMRR-20-1378-55292 Respiratory Outcome of Premature Newborns During the First Five Years of Life
NMRR-20-1187-53192 Whole exome sequencing of childhood interstitial lung disease in Malaysia
NMRr-21-237-58527 Reliability of FIBOD Balance System in assessing stability indices in healthy adults
NMRR-21-469-58687 Recurrent pneumonia in children: Clinical profile and risk factors
NMRR-22-00074-BVO Effect of COVID-19 pandemic to the hospital admission profile: Retrospective record review in a tertiary hospital
NMRR-22-02465-GBJ Cystic fibrosis and Primary Ciliary Dyskinesia in Malaysia: Clinical Characteristic and Genetic Profile
NMRR ID-22-02481-2II Indications, findings, and complications of Flexible Bronchoscopy on children in a tertiary hospital
NMRR-23-02109-0GW Bronchiectasis among children in Malaysia: A multicentre, observational study
NMRR-23-03180-O4X Causes of Recurrent Pneumonia
NMRR-23-00834-LVR Prevalence of antenatal tobacco smoke exposure among pregnant women: A cross-sectional study
NMRR-23-01271-WC2 Antenatal tobacco smoke exposure effect on newborns and post-natal smoke exposure intervention to respiratory illness in infants.
NMRR-24-01382-SEK Retrospective longitudinal study on interstitial lung diseases in Malaysia (RELOS-ILD)
NMRR-15-1121-26592 Phase 3, prospective, multi-center, open label study to investigate safety, immunogenicity, and hemostatic efficacy of PEGylated Factor VIII (BAX 855) in previously untreated patients (PUPs) < 6 years with severe hemophilia A (FV111 < 1%)
NMRR ID-21-01964-JHU A Phase 3, Double-blind, Randomized, Placebo-Controlled , Multicenter Study Evaluating the Efficacy and Safety of Mitapivat in Subject With Non-Transfusion-Dependent Alpha -or Beta-Thalassemia (ENERGIZE) 
NMRR ID-21-01965-4JL A Phase 3, Double-blind, Randomized, Placebo-Controlled , Multicenter Study Evaluating the Efficacy and Safety of Mitapivat in Subject With Non-Transfusion-Dependent Alpha -or Beta-Thalassemia (ENERGIZE-T) 
NMRR ID-21-01987-TBD A randomized, sham-controlled, double-blind study to evaluate the efficacy and safety of intrathecal (IT) OAV101 in patients with later onset Type 2 spinal muscular atrophy (SMA) who are ≥ 2 to < 18 years of age, treatment naive, sitting, and never ambulatory 
NMRR-21-1566-60179 A Phase 3, Multicenter, Randomized, Partially Blinded, Palivizumab-Controlled Study to Evaluate the Safety, Efficacy and Pharmacokinetics of MK-1654 in Infants and Children at Increased Risk for Severe RSV Disease. 
NMRR-18-3266-45336 Phase 3, Randomized, Open-label, Controlled, Multiple-Dose, Efficacy, Safety, Pharmacokinetic,and Pharmacodynamic Study of Etelcalcetide in Pediatric Subjects 28 days to < 18 Years of age With Secondary Hyperparathyroidism and Chronic Kidney Disease Receiving Maintenance Hemodialysis 
NMRR ID-23-00059-MKN Evasayil: A placebo-controlled tryial to evaluate the efficacy and safety of spesolimab in the treatment of patients with Netherton syndrome
NMRR ID-23-03026-I7U Long –term Follow up of Patients with Spinal Muscular Atrophy Treated with OAV101 IT or OAV101 IV in Clinical Trials
NMRR-24-00106-V9C Open-label study investigating efficacy, safety and pharmacokinetics of concizumab prophylaxis in children below 12 years with haemophilia A or B with or without inhibitors. 
NMRR-20-960-54712 An extension study to evaluate the long-term outcomes of subject who received treatment of retinopathy of prematury in study 20090 (Study 20275).

Services at CRC Hospital Tunku Azizah

CRC HTA provides the following services:

  • Research
    • Initiation of and direct involvement in research activities
    • Coordination, and be direct involvement with, research and innovation projects under Projek Inovasi dan Penyelidikan Kementerian Kesihatan Malaysia
    • Coordination, and be direct involvement with, multicentre research projects in Malaysia
    • Facilitating Clinical Research Malaysia (CRM) with Industry Sponsored Research (ISR) activities

 

  • Consultation
    • Provision of research consultation to ensure a good research proposal write-up with scientifically valid and ethically sound methodology
    • Aiding researchers on sample size calculation in order to get a significant result for their projects
    • Guiding researchers about registration with National Medical Research Registry (NMRR) as well as with the hospital and departments.
    • Giving statistical consultation to researchers in order to optimize the output of their research

 

  • Training
    • Provision of training for hospital and CRC staff, for example, workshops and seminars, in areas related to clinical research
    • Collaborating with other organizations on research-related training
    • Taking part in hospital Continuous Medical Education (CME) programs

 

  • Management 
    • Daily administrative activities related to research and to the hospital
    • Implementation of research and hospital standard operating procedures
    • Availability of meeting rooms for meetings related to clinical research

Meet Our Collaborators

Interdepartmental Collaborations:

  • Paediatric Department
  • Paediatric Surgery Department
  • Obstetrics and Gynaecology Department
  • Nursing Unit
  • Psychiatry Department
  • Radiology Department
  • Hospital Administrators
  • Pathology Department
  • Anaesthesiology Department
  • Physiotherapy Unit

Institutional Collaborations:

  • Institute for Medical Research (IMR)
  • Institut Perubatan Respiratori
  • Paediatric Departments from Multicentre Ministry of Health hospitals
  • Internal Medicine Departments from Multicentre Ministry of Health hospitals
  • Sektor Kawalan Tibi dan Kusta, Ministry of Health
  • Ministry of Health Community Clinics
  • Sports Medicine Unit, Hospital Kuala Lumpur
  • Radiology Department, Hospital Kuala Lumpur
  • National Cancer Institute, Ministry of Health
  • Prince Court Medical Centre
  • Borneo Medical Centre
  • KPJ Tawakkal KL Specialist

Hospital University Collaborations:

  • University of Malaya
  • Universiti Kebangsaan Malaysia
  • Universiti Putra Malaysia

International Collaborations:

  • The Global Health Research Unit on Respiratory Health (RESPIRE) Collaborators
  • The Queen’s Medical Research Institute, University of Edinburgh
  • PC-COS Children Study Group

Intitutional Collaborations

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Upcoming Activities

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CRC Hospital Tunku Azizah, Kuala Lumpur

Clinical Research Centre,
Hospital Tunku Azizah,
Jalan Raja Muda Abdul Aziz,
Kg Baru, 50300 Kuala Lumpur, Malaysia
 

Email: researchwchkl@moh.gov.my

Phone number: 03-2600 3000 ext. 2120/2123

 

ICR
National Institutes of Health (NIH)
Ministry of Health Malaysia
Institute For Clinical Research
Block B4, National Institutes of Health (NIH)
No.1, Jalan Setia Murni U13/52, Seksyen U13
40170 Shah Alam, Selangor Darul Ehsan
Malaysia
 
Phone: 603-3362 7700
Email: contact@crc.gov.my
 

NIH Official Portal

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