Institute for Clinical Research Official Portal

Clinical Research Centre

Hospital Seri Manjung
Perak

WhoWe Are

Clinical Research Centre Hospital Seri Manjung (CRC HSM) was established since 2011, with the collaboration of Clinical Research Malaysia. We aim to improve patients’ health through ethical and quality clinical research. We manage Investigator Initiated Research (IIR) as well as Industry-Sponsored Research (ISR). The availability of medical facilities and investigators at the site contribute to the increasing number of clinical research in Hospital Seri Manjung. In addition, there are ongoing research consultations throughout the year to assist our colleagues in conducting research, such as National Medical Research Register (NMRR) registration, protocol development, literature search, statistical analysis, manuscript write-up and assistance in submission for publication of research papers. We also provide research-related trainings such as Good Clinical Practice (GCP) Workshop, Introduction to Clinical Research (ICR) Workshop, Basic Biostatistics Workshop, Proposal Writing Workshop, Literature Search and Referencing Workshop, Scientific Writing Workshop, NMRR Registration Workshop, etc.

OurTeam

NAME POSITION QUALIFICATION EMAIL
Dr. Nga Shih Hang Head, Consultant Paediatrician
MBBS, MRCPCH
ngashihhang@gmail.com 
Dr. Farah binti Alwi Deputy Head, Emergency Physician MBChB, DrEmMed farahalwi23@gmail.com 
Norsarlizna bte Mat Sari Staff Nurse (Admin Manager) Bachelor of Nursing Science norsarlizna_hsm@yahoo.co.nz 
Dr. Ting Siew Ying Medical Officer MD t.xiuyin@gmail.com 
Chiew Shoen Chuen Pharmacist
BPharm chiewsc85@gmail.com 

 

InvestigatorsHighlight

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Head of CRC, Consultant Paediatrician, Hospital Seri Manjung (HSM

Email: ngashihhang@gmail.com 

MBBS, MRCPCH

Areas of interest: Paediatric Asthma, Diabetes, Neonatology

Awards and achievements:

  • Excellent Service Award, Ministry of Health Malaysia - 2006, 2011

Dr. Nga, who holds an MBBS and MRCPCH in Paediatrics, earned his GCP certification in 2006 and soon began his first Industry Sponsored Research (ISR). His subsequent ISRs have focused on paediatric asthma, Type 2 diabetes, and RSV infections. He is currently the head of the Clinical Research Centre at Hospital Seri Manjung, a 305-bed minor specialist hospital offering services in various fields including Internal Medicine, Obstetrics, Surgery, Paediatrics, and more. Dr. Nga has conducted local audits on topics such as neonatal intravenous cannulation, patient falls in paediatric wards, sexual abuse in suburban areas, and iron overload in thalassemia. He also published a case report on Refractory Kawasaki Disease in the Medical Journal of Malaysia.

Recent Publications

Research Work Involvement

  1. Oral Diosmectite reduces stool output and diarrhoea duration in children with acute watery diarrhoea
  2. Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma (as Country Coordinating PI)
  3. T2NOW: A 26-Week, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Parallel Group, Phase 3 Trial with a 26-Week Safety Extension Period Evaluating the Safety and Efficacy of Dapagliflozin 5 and 10 mg, and Saxagliptin 2.5 and 5 mg in Pediatric Patients with Type 2 Diabetes Mellitus Who Are Between 10 and Below 18 Years of Age
  4. ReViral: A Phase 2 Open-Label Study in Infants with REspiratory Syncytial VIRus Lower RespirAtory Tract Infection, Followed by a DoubLe-blind, Placebo controlled Part, to Evaluate the Safety, Tolerability, Pharmacokinetics and Antiviral Effect of RV521 (REVIRAL 1)
  5. MK 1654: A Phase 2b/3 Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-1654 in Healthy Pre-Term and Full-Term Infants
  6. A randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, safety, and tolerability of dexpramipexole administered orally for 52 weeks in participants with severe eosinophilic asthma (EXHALE-2)
  7. An Interventional, Phase 1b, Randomized, Double-Blind, Placebo-controlled , Multi-center, Dose-finding Study To Evaluate Safety, Tolerability and Pharmacokinetics Of SISUNATOVIR In Pediatric Participants up to age 60 months with Respiratory SyncitialVirus (RSV) Lower Respiratory Tract Infection (LRTI)

Project Highlights

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  Brief Educational Intervention on E-Cigarettes: Impact on Knowledge, Perception & Intention to Try among Secondary School Adolescents in Manjung District, Perak
  Aiming for Better Clinical Documentation by the Emergency & Trauma Department Team: A Quality Improvement Project
  Diagnosing Hypertriglyceridemic Acute Pancreatitis (HTGAP) with Urine Amylase: Case Report
  Assessment of Knowledge and Practice of Caretakers of Paediatric Patients on Storage of Oral Liquid Medications: A Multi-Centre Study
  Prevalence and Clinical Features of Pulmonary Embolism in Pregnancy and Puerperium: A Tertiary Hospital Report
  Audit on Management of Iron Overload in Transfusion Dependent Thalassemia (TDT) in Paediatric Ward of a District Specialist Hospital in Perak
  The Evaluation of Lipid Modifying Agents Prescribing Trend from 2015 to 2020 in Manjung District Perak : A Clinical Audit
  Cardiac Cephalgia - Headache of the Heart: Case Report
  Audit of Venous Thromboembolism (VTE) Prophylaxis Usage in Medical Wards of a District Specialist Hospital in Perak
  Attitudes and Beliefs to Use of Medical Cannabis among Malaysian's Doctors
  The Rate of Blood Culture Contamination and Common Organisms Isolated in Malaysian Public Hospitals
  A Descriptive Study of Neonatal Encephalopathy (NE) in the Neonatal Intensive Care Unit of Seri Manjung Hospital in Perak, A Minor Specialist Hospital in Malaysia
  Two Cases of Lethal Junctional Haemorrhage: A District General Hospital Experience
  COVID-19 Related Occupational Stress Perceived by Medical Officers in a Hospital in Northern Malaysia
  Factors Associated with Surgical Site Infection Post Appendectomy in a Tertiary District Hospital: A Two-Year Analysis
  Private vs Public Pharmacist: Patients' Experience on Medication Counselling
  Knowledge, Attitude and Practice of Pregnant Women Regarding Anaemia during Antenatal Visit at Kampar Health Clinic
  Sleep Disturbance in School-aged Children with Autistic Spectrum Disorder: Prevalence and Effect to Parental Stress in Penang, Malaysia
  Moral Distress among Healthcare Professionals in Malaysia during the COVID-19 Pandemic
  Are Malaysian Children Aware of Their Rights?
  D4325C00010 (ZENITH High Proteinuria)
A Phase III, Randomised, Multicentre, Double-blind Study to Evaluate the Efficacy, Safety, and Tolerability of Zibotentan/ Dapagliflozin Compared to Dapagliflozin Alone in Participants with Chronic Kidney Disease and High Proteinuria
  WA43966 (IMAGINATION)
A Phase III, Multicenter, Randomized, Double Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety Of RO7434656, an Antisense Inhibitor of Complement Factor B, in Patients with Primary IgA Nephropathy at High Risk of Progression
  70033093AFL3002 (LIBREXIA AF)
A Phase 3, Randomized, Double-Blind, Double-Dummy, Parallel Group, Active-Controlled Study to Evaluate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, versus Apixaban in Participants with Atrial Fibrillation
  NN9838-4942 (REDEFINE 3)
The Cardiovascular Safety and Efficacy of Cagrilintide 2.4 mg s.c. in Combination with Semaglutide 2.4 mg s.c. (CagriSema 2.4 mg/2.4 mg s.c.) Once-weekly in Participants with Established Cardiovascular Disease
  LG-GDCL010 (EURELIA 2)
A Randomized, Multi-regional, Double-blind, Double-dummy Parallel-group, Placebo and Allopurinol-controlled Phase 3 Study to Assess the Efficacy and Safety of Tigulixostat in Gout Patients with Hyperuricemia
  D6970C00002 (BAXHTN)
A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy and Safety of Baxdrostat in Participants with Uncontrolled Hypertension on Two or More Medications including Participants with Resistant Hypertension
  CKJX839D12302 (VICTORION-1 PREVENT)
A Randomized, Double-blind, Placebo-controlled Multicenter Study to Evaluate the Effect of Inclisiran on Preventing Major Adverse Cardiovascular Events in High-risk Primary Prevention Patients
  D9487C00001 (DIALIZE-Outcomes)
An International, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Arrhythmia-Related Cardiovascular Outcomes in Participants on Chronic Hemodialysis with Recurrent Hyperkalemia
  EX6018-4758 (ZEUS)
Effects of Ziltivekimab versus Placebo on Cardiovascular Outcomes in Participants with Established Atherosclerotic Cardiovascular Disease, Chronic Kidney Disease and Systemic Inflammation
  D9488C00001 (STABILIZE-CKD)
A Phase 3, International, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants with CKD and Hyperkalaemia or at Risk of Hyperkalaemia
  NN9838-4609 (REDEFINE 2)
Efficacy and Safety of Cagrilintide s.c. 2.4mg in Combination with Semaglutide s.c. 2.4mg (CagriSema s.c. 2.4mg/2.4mg) Once-weekly in Participants with Overweight or Obesity and Type 2 Diabetes
  KBP5074-3-001 (CLARION-CKD)
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of KBP-5074, a Mineralocorticoid Receptor Antagonist, in Subjects with Uncontrolled Hypertension Who Have Moderate or Severe (Stage 3b/4) Chronic Kidney Disease
  21177 (FIND-CKD)
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Phase 3 study to Investigate the Efficacy and Safety of FInerenone, in addition to Standard of Care, on the Progression of Kidney Disease in Patients with Non-Diabetic Chronic Kidney Disease

List of Publications associated with CRC HSM

Services at CRC Hospital Seri Manjung

CRC HSM provides training through workshops and consultations:

  • Research consultations:

     

    • Proposal/Protocol development 
    • Research question/objective hypothesis
    • Study design
    • Sample size planning
    • Sampling technique
    • Instrument/questionnaire
    • Statistical planning
    • Protocol review

     

    Assist with statistical software:

    • Data entry/management 
    • Data analysis
    • Statistical writing
    • Abstract/report writing
    • NMRR assistance
    • DG approval for presentation/publication
    • Institution approval

     

    Training: 

    • Good Clinical Practice (GCP) Workshop
    • Introduction to Clinical Research (ICR) Workshop
    • Basic Biostatistics Workshop
    • Proposal Writing Workshop
    • Literature Search and Referencing Workshop

-20 to -40°C Freezer

Voltage Regulator

Generator

IP Room

-80°C Freezer

Mini Laboratory

CCTV

Meeting Room

Pharmaceutical Fridge

Centrifuges

Temperature monitor

Document Storage Area

Further info on upcoming activities

CRC Hospital Seri Manjung, Perak

Clinical Research Centre,
Hospital Seri Manjung,
32040 Seri Manjung, Perak.
 

Main Phone: +605-689 6600 ext. 6639

 

 

ICR
National Institutes of Health (NIH)
Ministry of Health Malaysia
Institute For Clinical Research
Block B4, National Institutes of Health (NIH)
No.1, Jalan Setia Murni U13/52, Seksyen U13
40170 Shah Alam, Selangor Darul Ehsan
Malaysia
 
Phone: 603-3362 7700
Email: contact@crc.gov.my
 

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